This product is a gray-brown granules.
2. physical and chemical properties
The monensin sodium has the molecular formula: C36H61O11Na, molecular weight: 692.8. This product is insoluble in water and soluble in organic solvents such as methanol, ethanol and chloroform. Melting point: 267-269 ° C [Function] Antibiotics for chicken coccidiosis and beef cattle for growth. Good anticoccidial activity. It has no effect on the negative bacteria; but it has a certain inhibitory effect on Staphylococcus, Bacillus, Clostridium, Streptococcus, Mold (Planus, Candida). [Mode of action] Mainly used in early coccidia. The normal coccidial sporophyte and schizont cells have high potassium ion concentration and low sodium ion concentration (external cell). The cells perform ion osmotic pressure balance through reserve energy (external pumping sodium, internal pumping potassium) to stabilize the bacterial environment. . Monensin interferes with the normal exchange of sodium and potassium ions in coccidia cells, causing a large amount of sodium ions to enter the cells, resulting in a high intracellular concentration of sodium ions, an increase in osmotic pressure, and more water entering the coccidia. In order to eliminate excess sodium in the cells, the coccidia must use energy to pump excess sodium out of the pump, eventually causing limited energy to be used up; then the sodium-potassium ion exchange is interrupted and the cells expand, deform, rupture, and disintegrate. Monensin can affect rumen energy metabolism in ruminants, improve rumen fermentation, increase the ratio of propionic acid to acetic acid, reduce volatile fatty acids, reduce methane production, and improve protein utilization efficiency. Therefore, it can significantly improve the feed utilization and growth of ruminants.
No toxicity was administered at less than 121 ppm. At 3-5 times (363-605 ppm), the food intake decreased and the weight gain decreased. Significant mortality increased at 605 ppm, about 21%, while 363 ppm did not. It is highly toxic to Equine animals, with an LD50 of 2-3 mg/kg. The symptoms of poisoning are anorexia, movement disorders, intermittent sweating, and death. In combination with tiamulin and troleandomycin may be poisoned. [Residue] The ministerial standard stipulates that the drug holiday period is 5 days. The test proved that after 8 weeks of continuous feeding, the drug composition was not detected in all tissues after stopping for three days. The laying hens are stopped during laying, usually only for 16 weeks.
Good stability. Preservation in various feeds or for 3 months alone does not affect activity.
5. methods of use
Mixed feeding. Chicken, add 90-110g per 1000kg of feed; beef cattle, 200-360mg per head per day. All of the above are based on the active ingredient.
 Laying hens are banned during laying period; cows and equine animals in lactation are banned; use with tiamulin and oleandomycin is prohibited; contact with human skin and eyes is prohibited when mixing ingredients; 5 days off during drug holiday .
7 .storage methods
Sealed and stored in a dry place.
8 .product features
1. High stability and good control of coccidia. The drug is the first choice for rotation, and it is safe and stable for all poultry. 2. Improve feed efficiency. Monensin can help the broiler to go out in advance, improve the ratio of meat to meat, and has obvious economic benefits. 3. Inspire coccidia immunity.
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